This is a quick reference in the comic, but alludes to a very important plot point to the story. Kykeon is a substance only known to the ancients, which was likely a psychedelic substance that was held sacred.
Phil and Colin discover a cave, and manage to get Sophia mixed up into a crazy adventure into the unknown.
While on a class trip, two college students discover a secret dimension ruled by ancient philosophers, accidentally getting their teacher’s assistant (and Colin’s crush) possessed along the way. They must become enlightened (or fool everyone into thinking they are) to return back home.